Pesquisa | BVS Violência e Saúde

1.

TCF1-LEF1 co-expression identifies a multipotent progenitor cell (T_H2-MPP) across human allergic diseases.

Kratchmarov, Radomir; Djeddi, Sarah; Dunlap, Garrett; He, Wenqin; Jia, Xiaojiong; Burk, Caitlin M; Ryan, Tessa; McGill, Alanna; Allegretti, Jessica R; Kataru, Raghu P; Mehrara, Babak J; Taylor, Erin M; Agarwal, Shailesh; Bhattacharyya, Neil; Bergmark, Regan W; Maxfield, Alice Z; Lee, Stella; Roditi, Rachel; Dwyer, Daniel F; Boyce, Joshua A; Buchheit, Kathleen M; Laidlaw, Tanya M; Shreffler, Wayne G; Rao, Deepak A; Gutierrez-Arcelus, Maria; Brennan, Patrick J.

Nat Immunol ; 25(5): 902-915, 2024 May.

Artigo em Inglês | MEDLINE | ID: mdl-38589618

2.

SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues.

Ziegler, Carly G K; Allon, Samuel J; Nyquist, Sarah K; Mbano, Ian M; Miao, Vincent N; Tzouanas, Constantine N; Cao, Yuming; Yousif, Ashraf S; Bals, Julia; Hauser, Blake M; Feldman, Jared; Muus, Christoph; Wadsworth, Marc H; Kazer, Samuel W; Hughes, Travis K; Doran, Benjamin; Gatter, G James; Vukovic, Marko; Taliaferro, Faith; Mead, Benjamin E; Guo, Zhiru; Wang, Jennifer P; Gras, Delphine; Plaisant, Magali; Ansari, Meshal; Angelidis, Ilias; Adler, Heiko; Sucre, Jennifer M S; Taylor, Chase J; Lin, Brian; Waghray, Avinash; Mitsialis, Vanessa; Dwyer, Daniel F; Buchheit, Kathleen M; Boyce, Joshua A; Barrett, Nora A; Laidlaw, Tanya M; Carroll, Shaina L; Colonna, Lucrezia; Tkachev, Victor; Peterson, Christopher W; Yu, Alison; Zheng, Hengqi Betty; Gideon, Hannah P; Winchell, Caylin G; Lin, Philana Ling; Bingle, Colin D; Snapper, Scott B; Kropski, Jonathan A; Theis, Fabian J.

Cell ; 181(5): 1016-1035.e19, 2020 05 28.

Artigo em Inglês | MEDLINE | ID: mdl-32413319

3.

Glucagon-like Peptide-1 Receptor Pathway Attenuates Platelet Activation in Aspirin-Exacerbated Respiratory Disease.

Foer, Dinah; Amin, Taneem; Nagai, Jun; Tani, Yumi; Feng, Chunli; Liu, Tao; Newcomb, Dawn C; Lai, Juying; Hayashi, Hiroaki; Snyder, William E; McGill, Alanna; Lin, Anabel; Laidlaw, Tanya M; Niswender, Kevin D; Boyce, Joshua A; Cahill, Katherine N.

J Immunol ; 211(12): 1806-1813, 2023 12 15.

Artigo em Inglês | MEDLINE | ID: mdl-37870292

4.

IL-4Rα signaling promotes barrier-altering oncostatin M and IL-6 production in aspirin-exacerbated respiratory disease.

Chen, Chongjia C; Buchheit, Kathleen M; Lee, Pui Y; Brodeur, Kailey E; Sohail, Aaqib; Cho, Laura; Baloh, Carolyn; Balestrieri, Barbara; Derakhshan, Mina; Feng, Chunli; Boyce, Joshua A; Dwyer, Daniel; Laidlaw, Tanya M.

J Allergy Clin Immunol ; 2024 May 02.

Artigo em Inglês | MEDLINE | ID: mdl-38704098

5.

Macrophage P2Y6 Receptor Signaling Selectively Activates NFATC2 and Suppresses Allergic Lung Inflammation.

Nagai, Jun; Lin, Junrui; Boyce, Joshua A.

J Immunol ; 209(12): 2293-2303, 2022 12 15.

Artigo em Inglês | MEDLINE | ID: mdl-36307120

6.

Allergic inflammatory memory in human respiratory epithelial progenitor cells.

Ordovas-Montanes, Jose; Dwyer, Daniel F; Nyquist, Sarah K; Buchheit, Kathleen M; Vukovic, Marko; Deb, Chaarushena; Wadsworth, Marc H; Hughes, Travis K; Kazer, Samuel W; Yoshimoto, Eri; Cahill, Katherine N; Bhattacharyya, Neil; Katz, Howard R; Berger, Bonnie; Laidlaw, Tanya M; Boyce, Joshua A; Barrett, Nora A; Shalek, Alex K.

Nature ; 560(7720): 649-654, 2018 08.

Artigo em Inglês | MEDLINE | ID: mdl-30135581

7.

Association of GLP-1 Receptor Agonists with Chronic Obstructive Pulmonary Disease Exacerbations among Patients with Type 2 Diabetes.

Foer, Dinah; Strasser, Zachary H; Cui, Jing; Cahill, Katherine N; Boyce, Joshua A; Murphy, Shawn N; Karlson, Elizabeth W.

Am J Respir Crit Care Med ; 208(10): 1088-1100, 2023 Nov 15.

Artigo em Inglês | MEDLINE | ID: mdl-37647574

8.

Updates on immune mechanisms in aspirin-exacerbated respiratory disease.

Laidlaw, Tanya M; Boyce, Joshua A.

J Allergy Clin Immunol ; 151(2): 301-309, 2023 02.

Artigo em Inglês | MEDLINE | ID: mdl-36184313

9.

Trial of thromboxane receptor inhibition with ifetroban: TP receptors regulate eicosanoid homeostasis in aspirin-exacerbated respiratory disease.

Laidlaw, Tanya M; Buchheit, Kathleen M; Cahill, Katherine N; Hacker, Jonathan; Cho, Laura; Cui, Jing; Feng, Chunli; Chen, Chongjia C; Le, Meghan; Israel, Elliot; Boyce, Joshua A.

J Allergy Clin Immunol ; 152(3): 700-710.e3, 2023 09.

Artigo em Inglês | MEDLINE | ID: mdl-37068712

10.

Type 2 inflammation drives an airway basal stem cell program through insulin receptor substrate signaling.

Wang, Xin; Hallen, Nils R; Lee, Minkyu; Samuchiwal, Sachin; Ye, Qihua; Buchheit, Kathleen M; Maxfield, Alice Z; Roditi, Rachel E; Bergmark, Regan W; Bhattacharyya, Neil; Ryan, Tessa; Gakpo, Deb; Raychaudhuri, Soumya; Dwyer, Dan; Laidlaw, Tanya M; Boyce, Joshua A; Gutierrez-Arcelus, Maria; Barrett, Nora A.

J Allergy Clin Immunol ; 151(6): 1536-1549, 2023 06.

Artigo em Inglês | MEDLINE | ID: mdl-36804595

11.

Advances in mast cell biology.

Boyce, Joshua A.

J Allergy Clin Immunol ; 149(6): 1919-1925, 2022 06.

Artigo em Inglês | MEDLINE | ID: mdl-35427642

12.

Defining mast cell differentiation and heterogeneity through single-cell transcriptomics analysis.

Derakhshan, Tahereh; Boyce, Joshua A; Dwyer, Daniel F.

J Allergy Clin Immunol ; 150(4): 739-747, 2022 10.

Artigo em Inglês | MEDLINE | ID: mdl-36205448

13.

Mediator production and severity of aspirin-induced respiratory reactions: Impact of sampling site and body mass index.

Cahill, Katherine N; Wu, Pingsheng; Milne, Ginger L; Amin, Taneem; Singer, Joseph; Murphy, Katherine; Lewis, Erin; Gapko, Deborah; Boyce, Joshua A; Buchheit, Katherine M; Laidlaw, Tanya M.

J Allergy Clin Immunol ; 150(1): 170-177.e6, 2022 07.

Artigo em Inglês | MEDLINE | ID: mdl-35026207

14.

INSIGHTS INTO THE REGULATION OF MAST CELL FUNCTION IN TYPE 2 INFLAMMATION.

Boyce, Joshua A.

Trans Am Clin Climatol Assoc ; 132: 92-103, 2022.

Artigo em Inglês | MEDLINE | ID: mdl-36196164

15.

Leukotriene D₄ paradoxically limits LTC₄-driven platelet activation and lung immunopathology.

Liu, Tao; Barrett, Nora A; Nagai, Jun; Lai, Juying; Feng, Chunli; Boyce, Joshua A.

J Allergy Clin Immunol ; 148(1): 195-208.e5, 2021 07.

Artigo em Inglês | MEDLINE | ID: mdl-33285161

16.

IL-5Rα marks nasal polyp IgG4- and IgE-expressing cells in aspirin-exacerbated respiratory disease.

Buchheit, Kathleen M; Dwyer, Daniel F; Ordovas-Montanes, Jose; Katz, Howard R; Lewis, Erin; Vukovic, Marko; Lai, Juying; Bankova, Lora G; Bhattacharyya, Neil; Shalek, Alex K; Barrett, Nora A; Boyce, Joshua A; Laidlaw, Tanya M.

J Allergy Clin Immunol ; 145(6): 1574-1584, 2020 06.

Artigo em Inglês | MEDLINE | ID: mdl-32199912

17.

KIT Inhibition by Imatinib in Patients with Severe Refractory Asthma.

Cahill, Katherine N; Katz, Howard R; Cui, Jing; Lai, Juying; Kazani, Shamsah; Crosby-Thompson, Allison; Garofalo, Denise; Castro, Mario; Jarjour, Nizar; DiMango, Emily; Erzurum, Serpil; Trevor, Jennifer L; Shenoy, Kartik; Chinchilli, Vernon M; Wechsler, Michael E; Laidlaw, Tanya M; Boyce, Joshua A; Israel, Elliot.

N Engl J Med ; 376(20): 1911-1920, 2017 05 18.

Artigo em Inglês | MEDLINE | ID: mdl-28514613

18.

Type 2 Cysteinyl Leukotriene Receptors Drive IL-33-Dependent Type 2 Immunopathology and Aspirin Sensitivity.

Liu, Tao; Barrett, Nora A; Kanaoka, Yoshihide; Yoshimoto, Eri; Garofalo, Denise; Cirka, Haley; Feng, Chunli; Boyce, Joshua A.

J Immunol ; 200(3): 915-927, 2018 02 01.

Artigo em Inglês | MEDLINE | ID: mdl-29282304

19.

Unique Effect of Aspirin Therapy on Biomarkers in Aspirin-exacerbated Respiratory Disease. A Prospective Trial.

Cahill, Katherine N; Cui, Jing; Kothari, Parul; Murphy, Katherine; Raby, Benjamin A; Singer, Joseph; Israel, Elliot; Boyce, Joshua A; Laidlaw, Tanya M.

Am J Respir Crit Care Med ; 200(6): 704-711, 2019 09 15.

Artigo em Inglês | MEDLINE | ID: mdl-30978291

20.

Aspirin sensitivity: Lessons in the regulation (and dysregulation) of mast cell function.

Boyce, Joshua A.

J Allergy Clin Immunol ; 144(4): 875-881, 2019 10.

Artigo em Inglês | MEDLINE | ID: mdl-31587797

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TCF1-LEF1 co-expression identifies a multipotent progenitor cell (T_H2-MPP) across human allergic diseases.

SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues.

Glucagon-like Peptide-1 Receptor Pathway Attenuates Platelet Activation in Aspirin-Exacerbated Respiratory Disease.

IL-4Rα signaling promotes barrier-altering oncostatin M and IL-6 production in aspirin-exacerbated respiratory disease.

Macrophage P2Y6 Receptor Signaling Selectively Activates NFATC2 and Suppresses Allergic Lung Inflammation.

Allergic inflammatory memory in human respiratory epithelial progenitor cells.

Association of GLP-1 Receptor Agonists with Chronic Obstructive Pulmonary Disease Exacerbations among Patients with Type 2 Diabetes.

Updates on immune mechanisms in aspirin-exacerbated respiratory disease.

Trial of thromboxane receptor inhibition with ifetroban: TP receptors regulate eicosanoid homeostasis in aspirin-exacerbated respiratory disease.

Type 2 inflammation drives an airway basal stem cell program through insulin receptor substrate signaling.

Advances in mast cell biology.

Defining mast cell differentiation and heterogeneity through single-cell transcriptomics analysis.

Mediator production and severity of aspirin-induced respiratory reactions: Impact of sampling site and body mass index.

INSIGHTS INTO THE REGULATION OF MAST CELL FUNCTION IN TYPE 2 INFLAMMATION.

Leukotriene D₄ paradoxically limits LTC₄-driven platelet activation and lung immunopathology.

IL-5Rα marks nasal polyp IgG4- and IgE-expressing cells in aspirin-exacerbated respiratory disease.

KIT Inhibition by Imatinib in Patients with Severe Refractory Asthma.

Type 2 Cysteinyl Leukotriene Receptors Drive IL-33-Dependent Type 2 Immunopathology and Aspirin Sensitivity.

Unique Effect of Aspirin Therapy on Biomarkers in Aspirin-exacerbated Respiratory Disease. A Prospective Trial.

Aspirin sensitivity: Lessons in the regulation (and dysregulation) of mast cell function.